Regenerative Science
Long before it reached skincare, this DNA-based active worked quietly in clinics, helping the body repair itself. Now it's part of your daily routine.
Cellular Hydration
PDRN holds water at a cellular level, so hydration actually lasts and the look of dullness fades.
Grown from Rose
Sourced from rose instead of pulled from the sea, then developed in the lab through regenerative science.
— Benefits of PDRN
Hydration that lasts, holds water at a cellular level, so it doesn't just sit on the surface - it lasts.
Visibly smooths, works with skin's own repair process to reduce the look of fine lines and improve firmness.
Fades dullness, helps reveal smoother, more even-toned, more radiant-looking skin underneath.
FAQs
Everything you need to know about PDRN
PDRN (polydeoxyribonucleotide) is a DNA-based active originally used in regenerative medicine to help the body repair and calm itself. At OGB, it's the foundation of the PDRN Peptide Tanning Mist and PDRN Multi-Peptide Eye Complex.
PDRN is derived from rose, not the marine sources (like salmon or trout DNA) that most PDRN on the market is extracted from. Grown from rose rather than pulled from the sea, it spent years working quietly behind clinic doors as part of regenerative medicine, used to support tissue repair at a cellular level, before OGB brought it directly from the lab into skincare. Same active, same DNA-based science, just sourced differently
Yes. Both the PDRN Peptide Tanning Mist and PDRN Multi-Peptide Eye Complex are vegan and cruelty-free, no animal-derived ingredients, and never tested on animals.
It works with skin's natural repair process, holds water at a cellular level so hydration actually lasts, and helps fade the look of dullness over time.
They work in different ways rather than doing the same job. Retinol speeds up cell turnover, hyaluronic acid draws in surface moisture, and peptides send signals that support collagen. PDRN works differently again, supporting the skin's own repair process and helping it hold onto moisture at a cellular level. In the Eye Complex, PDRN, retinol, peptides and hyaluronic acid are combined so they work together rather than overlapping.
Yes. PDRN works differently to most other actives, supporting the skin's repair process and helping it hold onto moisture, so it layers well with retinol, vitamin C and other actives rather than competing with them for the same job. The PDRN Multi-Peptide Eye Complex is already formulated with PDRN alongside retinol, peptides and hyaluronic acid, so no extra caution is needed there. If you're introducing a separate active elsewhere in your routine, like a standalone vitamin C serum, we recommend introducing one new product at a time so you can see how your skin responds.
As with any new active in your routine, if you're pregnant, breastfeeding or have any health concerns, we recommend speaking with your doctor before adding PDRN to your skincare routine. If you have sensitive skin, introduce it gradually, start with fewer applications per week and increase frequency as your skin adjusts, discontinuing use if irritation occurs. The PDRN Multi-Peptide Eye Complex also contains retinol, which carries its own specific guidance, see that product's FAQ for details.
— WHAT'S THE DIFFERENCE
Grown from rose.
Built on science.
What sets our PDRN Peptide Tanning Mist apart from our Collagen Serum Mist
Collagen Serum
Mist
PDRN
Peptide Tanning Mist
Key Actives
5% hydrolyzed collagen, niacinamide, grape see extract, hyaluronic acid
PDRN, peptides, hydrolyzed collagen
Best For
Daily hydration + instant glow
Gradual, natural sun-kissed tan + skin care
Tan
No
Yes
Texture
Lightweight, non-sticky mist
Ultra-fine, refreshing mist
When to Use
After cleansing, before makeup, or anytime as a refresh
Morning or evening, before your routine, or as the last step
Skin Benefits
Less dullness, plumper and smoother complexion
Smoother, firmer, more radiant-looking skin
— WHAT'S THE DIFFERENCE
Eye lift.
Powered by PDRN.
What sets our PDRN Multi-Peptide Eye Complex apart from our Miracle Eye Cream
Miracle Eye Cream
PDRN Multi-Peptide
Eye Complex
Key Actives
Plant-based collagen, hyaluronic acid, shea butter, soybean extract, Vitamin C, licorice root extract
PDRN, 15 Peptides, retinol, niacinamide, ceramides, squalene, 3 forms of hyaluronic acid
Best For
Everyday hydration and
cared-for eye contour
Targeted, next-level eye lifting treatment
Frequency
Daily
1-2x per week, building up gradually
Helps
Fine lines, dark circles,
hydrates, softens and firms
Fine lines, dark circles and puffiness
Device/Tool
None
Cooling + vibrating metal applicator, massages while it absorbs